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| Titel: |
A study of chemicals in the wood and associated industries for the selection of candidates for carcinogen bioassay |
| Auteur: |
Sigman, C. C. Helmes, C. T. Fay, J. R. Lundquist, P. L. Perry, L. R. |
| Verschenen in: |
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering |
| Paginering: | Jaargang 19 (1984) nr. 5 pagina's 533-577 |
| Jaar: |
1984-07 |
| Inhoud: |
Naturally-occurring wood chemicals were studied in order to nominate chemicals to the National Cancer Institute's Chemical Selection Working Group as candidates for carcinogenesis bioassay. After application of several qualifying criteria relating to previous, current, or planned carcinogenicity tests and to verification of the identity and occurrences in wood, the preliminary candidate list of approximately 300 compounds was reduced to a final candidate list of 248 chemicals. Based on consideration of possible carcinogenic activity and evidence indicating potential exposure, the following 11 chemicals were nominated: abietic acid, cardol and urushiol (as a pair representing alkenyl/alkanyl cate-chols), coniferyl aldehyde, ellagic acid, kaempferol, lapachol, 4-methoxydalbergione, podophyllotoxin, pterostilbene, and α-terpineol. Although they are naturally-occurring, two of these chemicals, abietic acid and α-terpineol, were nominated primarily on the basis of their commercial significance. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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