Mutagenicity screening of twenty-five cosmetic ingredients with the salmonella/microsome test
Titel:
Mutagenicity screening of twenty-five cosmetic ingredients with the salmonella/microsome test
Auteur:
Blevins, R. D. Taylor, D. E.
Verschenen in:
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
Paginering:
Jaargang 17 (1982) nr. 2 pagina's 217-239
Jaar:
1982
Inhoud:
The possible mutagenic activity of twney-five cosmetic ingredients was investigated using the Salmonella histidine auxotrophs hisTA98, hisTA100, his TA1535, hisTA1537 and hisTA1538. All twenty-five cosmetic ingredients were subjected to the spot test, a qualitative form of the Salmonella/microsome test. Nine of the twenty-five cosmetic ingredients demonstrated potential mutagenicity in the spot testing and were further examined in plate incorporation tests, a quantitative form of the Salmonella/microsome test. Only one tested cosmetic ingredient, DEA Laureth Sulfate, gave positive mutagenic results in the plate incorporation test.
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