Cesium in mammals: Acute toxicity, organ changes and tissue accumulation
Titel:
Cesium in mammals: Acute toxicity, organ changes and tissue accumulation
Auteur:
Pinsky, Carl Bose, Ranjan Taylor, J. R. McKee, Jasper S. C. Lapointe, Claude Birchall, James
Verschenen in:
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering
Paginering:
Jaargang 16 (1981) nr. 5 pagina's 549-567
Jaar:
1981
Inhoud:
The acute toxicity of cesium given intraperitoneally (IP) as CsCl in mice is characterized by autonomic upset and by a multiphasic excitant-depressant action on the central nervous system. The predominantly depressant action can progress to respiratory embarassment, cyanosis, spinal convulsions and death. Light microscopy of mice treated with 2.0 mEq Cs+ kg-1 IP for 14 days showed lymphoid hyperplasia in small intestine. Measurement of tissue cesium by the proton-induced x-ray emission (PIXE) technique is convenient and reproducible. Cesium displays a generalized bioactivity that merits further study.