|
| << previous | next >> |
Journal description
All volumes of the corresponding journal
All issues of the corresponding volume
All articles of the corresponding issues
Details for article 15 of 178 found articles
| Title: |
A New Synthesis of 3-Deoxy-D-Manno-Octulosonic Acid (KDO) From D-Mannose Via Condensation of Dioxene |
| Author: |
Horito, Shigcomi Amano, Masayo Hashimoto, Hironobu |
| Appeared in: |
Journal of carbohydrate chemistry |
| Paging: | Volume 8 (1989) nr. 4 pages 681-684 |
| Year: |
1989-09-01 |
| Contents: |
The title compound has long been known as an essential component of lipopolysaccharides (LPS) and capsular polysaccharides which exist in the outer membrane of Gram-negative bacteria. KDO has attracted additional attention as a consequence of some remarkable discoveries; i) mutants unable to produce KDO are non-viable.1 ii) KDO is not present in mammalian cells,2 iii) the 2-deoxy analog of β-KDO represents a new class of synthetic antimicrobial agent.3,4 Although syntheses of KDO have been reported by many groups,5-8 a more efficient synthetic method endowed with the potential for synthesis of not only complex glycoconjugates but also biologically significant analogs is required. |
| Publisher: |
Taylor & Francis |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 15 of 178 found articles
| << previous | next >> |