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Details for article 83 of 252 found articles
| Title: |
Galactose-Phosphonates as Mimetics of the Sialyltransfer by Trypanosomal Sialidases |
| Author: |
Busse, Heike Hakoda, Mitsuru Stanley, Matthew Streicher, Hansjorg |
| Appeared in: |
Journal of carbohydrate chemistry |
| Paging: | Volume 26 (2007) nr. 3 pages 159-194 |
| Year: |
2007-04 |
| Contents: |
In an attempt to find competitive inhibitors of the trans-sialidase of the pathogen Trypanosoma cruzi, we have synthesized conjugates of carbocyclic sialylmimetics (e.g., cyclohexenephosphonates) and galactose derivatives. A trans-sialidase inhibition assay revealed an interesting preference for ethylidene-spacered conjugates involving the 3-position of the sugar. |
| Publisher: |
Taylor & Francis |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 83 of 252 found articles
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