SYNTHESIS OF PVA AND DEXTRAN DERIVATIVES 2,4-D ADDUCTS. INFLUENCE OF THE PRESENCE OF A SPACER GROUP ON THE BIOACTIVE CONTROLLED RELEASE BEHAVIOR
Titel:
SYNTHESIS OF PVA AND DEXTRAN DERIVATIVES 2,4-D ADDUCTS. INFLUENCE OF THE PRESENCE OF A SPACER GROUP ON THE BIOACTIVE CONTROLLED RELEASE BEHAVIOR
Auteur:
Bermello, J. Coro Napoles, M. N. Lores Allonso, F. Arranz
Verschenen in:
International journal of polymeric materials
Paginering:
Jaargang 51 (2002) nr. 8 pagina's 675-683
Jaar:
2002-08
Inhoud:
Polymeric systems for controlled release of 2,4-D acid were prepared using a biodegradable substance. Chloroacetylated dextran can be derivatized with 2,4-dichlorophenoxyacetic acid (2,4-D) by direct reaction with the potassium salt of 2,4-D. The release of 2,4-D linked to both supports is dependent on the temperature, pH value as well as on the hydrophilic/hydrophobic balance of the polymer. The presence of a spacer group in the molecule is also important and it is closely related to the hydrophobity of the system.