Digitale Bibliotheek
Sluiten Bladeren door artikelen uit een tijdschrift
 
<< vorige    volgende >>
     Tijdschrift beschrijving
       Alle jaargangen van het bijbehorende tijdschrift
         Alle afleveringen van het bijbehorende jaargang
           Alle artikelen van de bijbehorende aflevering
                                       Details van artikel 11 van 17 gevonden artikelen
 
 
  Models of Simultaneous Transport of Water and Drugs in Hydrophilic Polymer Systems
 
 
Titel: Models of Simultaneous Transport of Water and Drugs in Hydrophilic Polymer Systems
Auteur: Polishchuk, A. Ya.
Verschenen in: International journal of polymeric materials
Paginering: Jaargang 25 (1994) nr. 1-2 pagina's 37-47
Jaar: 1994-04-01
Inhoud: Different models have been developed in order to predict the behavior of systems consisting of hydrophilic polymer, water, and drug. The first model deals with the so-called matrix system of controlled drug release and describes the simultaneous transport of water and drug in swelling glassy polymers. The dependencies of physical/chemical parameters on the concentation of water, drug and on the mechanical properties of the polymer are used for justification and prediction of corresponding experimental results. The method of calculating the physical/chemical parameters is based on an experimental investigation of the structure of the polymer and the diffusion-kinetic process. The main aim of the development of the other model is to predict the mechanism and velocity of drug release in “reservoir polymer systems” for which the sorption and diffusion properties of water transport through a polymer membrane are most important. The main steps of drug release have been shown, and various dependencies of the diffusion coefficients have been studied in order to predict their influence on the mechanism and velocity of drug release.
Uitgever: Taylor & Francis
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details van artikel 11 van 17 gevonden artikelen
 
<< vorige    volgende >>
 
 Koninklijke Bibliotheek - Nationale Bibliotheek van Nederland