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Details van artikel 4 van 10 gevonden artikelen
| Titel: |
Immunologic and other biological parameters as a function of smoking status and of residence in areas differing in terms of air pollution |
| Auteur: |
Van Larebeke, Nik Husson, Bernard De Coen, Wim Pluygers, Eric |
| Verschenen in: |
International journal of environmental health research |
| Paginering: | Jaargang 13 (2003) nr. 1 pagina's 55-69 |
| Jaar: |
2003-03 |
| Inhoud: |
In the industrial region of La Louviere (Belgium), healthy persons, presenting at a consultation of preventive medicine, showed differences as a function of smoking and of residence in one of four areas differing in sources of emissions, population density and green zones. Smokers had significantly (P≤0.05) more leukocytes μl-1, neutrophils μl-1, CD3+ lymphocytes (lys) μl-1, CD4+ lys μl-1, CD25+ lys μl-1, higher CD4/CD8 ratio's and higher carcino-embryonic antigen serum levels but significantly lower IgG immunoglobulin and serum carotene levels than non-smokers. Compared to persons living in the 'Peripheral area', and after correction for sex, smoking status and age, persons living in the more polluted areas showed significantly more CD3+CD56+ lys μl-1. Although about the same mean value for the CD4/CD8 ratio was found for the more polluted areas, a higher percentage of their residents showed a ratio that was either <1 or ≥2.25, significantly so for the Power Station-Landfill area. A non-significant but consistent trend towards higher lymphocyte and CD8 lys counts and higher complement C3c serum levels further suggested an association between residence in a more polluted area and immunologic features. The number of CD3+CD56+ lys μl-1, reported to be increased in cancer patients, showed a negative correlation with the CD4/CD8 ratio (r2=0.132, P<0.0001). |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 4 van 10 gevonden artikelen
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