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  The Influence of Age on Intestinal Dipeptidyl Peptidase IV (DPP IV/CD26), Disaccharidases, and Alkaline Phosphatase Enzyme Activity in C57BL/6 Mice
 
 
Titel: The Influence of Age on Intestinal Dipeptidyl Peptidase IV (DPP IV/CD26), Disaccharidases, and Alkaline Phosphatase Enzyme Activity in C57BL/6 Mice
Auteur: Detel, Dijana
Baticic, Lara
Varljen, Jadranka
Verschenen in: Experimental aging research
Paginering: Jaargang 34 (2008) nr. 1 pagina's 49-62
Jaar: 2008-01
Inhoud: The objective of this study was to determine and describe the age-related changes in intestinal brush border membrane enzyme activities that occur in C57Bl/6 mice. Specifically, jejunal, duodenal, and ileal dipeptidyl peptidase IV/CD26, disaccharidase (lactase, sucrase, and maltase), and alkaline phosphatase activities were determined. A significant correlation between analyzed intestinal brush border membrane enzyme activities and animal age was found. Our study revealed that intestinal dipeptidyl peptidase IV/CD26, lactase, sucrase, maltase, and alkaline phosphatase activities decline significantly with age (p < .05). Nevertheless, the horizontal (duodenum to ileum) enzyme activity patterns are not affected by age.
Uitgever: Routledge
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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