Digitale Bibliotheek
Sluiten Bladeren door artikelen uit een tijdschrift
 
<< vorige    volgende >>
     Tijdschrift beschrijving
       Alle jaargangen van het bijbehorende tijdschrift
         Alle afleveringen van het bijbehorende jaargang
           Alle artikelen van de bijbehorende aflevering
                                       Details van artikel 11 van 12 gevonden artikelen
 
 
  NON-STATIONARY DRYING KINETICS IN A BATCH PHARMACEUTICAL FLUIDIZED BED COATING PROCESS
 
 
Titel: NON-STATIONARY DRYING KINETICS IN A BATCH PHARMACEUTICAL FLUIDIZED BED COATING PROCESS
Auteur: Heinrich, S.
Mori, L.
Wostheinrich, K.
Schmidt, P.C.
Verschenen in: Drying technology
Paginering: Jaargang 18 (2000) nr. 9 pagina's 2065-2090
Jaar: 2000-10-01
Inhoud: In this paper a physically based mathematical model for the description of particle wetting, temperature and humidity characteristics during a non-stationary fluidized bed spray-drying of granules or during a non-stationary fluidized bed coating in a Huttlin®-Kugelcoater HKC 05-TJ is introduced. Using this model it is possible to calculate the humidity and temperature of the air, the degree of particle wetting, the temperatures of both the liquid layer and the particles under consideration and the influence of the wall of the apparatus and its surroundings. The effects of start-up and shut-down processes on the results as well as the time dependence of the discontinuous process with varying process parameters such as the amount of liquid sprayed in and its temperature, the amount of fluidising air and its temperature are simulated and the results were compared with those obtained experimentally using a Huttlin -Kugelcoater HKC 05-TJ. Furthermore, the growth of the bed and the increase of particle masses during a discontinuous coating and granulation processes were taken into account in a simplified manner.
Uitgever: Taylor & Francis
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details van artikel 11 van 12 gevonden artikelen
 
<< vorige    volgende >>
 
 Koninklijke Bibliotheek - Nationale Bibliotheek van Nederland