|
| << vorige | volgende >> |
Tijdschrift beschrijving
Alle jaargangen van het bijbehorende tijdschrift
Alle afleveringen van het bijbehorende jaargang
Alle artikelen van de bijbehorende aflevering
Details van artikel 20 van 22 gevonden artikelen
| Titel: |
Randomized play the winner clinical trials |
| Auteur: |
Cornell, Richard G. Landenberger, Bryce D. left, Robert H Bart |
| Verschenen in: |
Communications in statistics |
| Paginering: | Jaargang 15 (1986) nr. 1 pagina's 159-178 |
| Jaar: |
1986 |
| Inhoud: |
Tables are presented for the design of randomized play-the winner (RPW) clinical trials to achieve a high probability of selection of the best of two treatments and a balance between the expected number of patients on the inferior treatment and an index of possible patient selection bias. Included is a method of accelerating the divergence of the treatment allocation probabilities as the patient responses accumulate in favor of one treatment over the other. An application of the RPW approach to a clinical trial on the treatment of respiratory distress in newborn infants is discussed. The trial is interpreted in terms of the posterior probability of correct selection given the observed results. A modified design criterion is suggested based upon the selection of a new treatment over a standard control only when the posterior probability of correct seclection is high |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 20 van 22 gevonden artikelen
| << vorige | volgende >> |