Sleep recordings in the elderly before and after usage of a geriatric preparation
Titel:
Sleep recordings in the elderly before and after usage of a geriatric preparation
Auteur:
Kerkhof, G. A. Middelkoop, H. A. M. Van der Hoeve, R. Kamphuisen, H. A. C. Kemp, B.
Verschenen in:
Biological rhythm research
Paginering:
Jaargang 20 (1989) nr. 1 pagina's 57-63
Jaar:
1989-02
Inhoud:
It was hypothesized that the daily intake of a geriatric preparation containing vitamins, minerals, trace elements and ginseng, would strengthen the sleep-wake rhythm and thus have a positive influence upon characteristics of sleep. A total of 32 subjects (age 61 -92, mean 78 yr, 23 females) was recruited from a local elderly home. In a double-blind procedure 16 subjects received the geriatric preparation for a period of 10 weeks, while the other 16 subjects received a placebo. Before treatment, a 48-hour polygraphic home-recording was made of the EEG, and - during sleep - of the chin EMG, the EOG and respiration. At the end of the treatment period ( 10 weeks later) this recording was repeated. After exclusion of low-quality recordings, the data of two groups of 10 subjects each were analyzed. The results show a significantly increased percentage of REM sleep for the experimental group after treatment, and a similar trend for Slow Wave Sleep. Moreover, inspection of the spectra of the 24-hour EEG recordings suggests an increased circadian amplitude of the low-frequency EEG.