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| Titel: |
A circannual rhythm in rubella antibody titers |
| Auteur: |
Rosenblatt, Leon S. Shifrine, Moshe Hetherington, Norriss W. Paglierioni, Theresa MacKenzie, Malcolm R. |
| Verschenen in: |
Biological rhythm research |
| Paginering: | Jaargang 13 (1982) nr. 1 pagina's 81-88 |
| Jaar: |
1982-02 |
| Inhoud: |
Rubella antibody titers were assayed from 191 blood samples taken during seven years (1973-1979) from a human female who had contracted German measles in 1965. The antibody dilutions, transformed to integers, fit a first-order harmonic function with an assumed period of 365 days. The levels about which the titers oscillated decreased from 1973 to 1975 and remained stable thereafter. Amplitudes averaged 31% on either side of the level of oscillation. At certain times of the years 1977-1979 at the trough of the rhythm the subject would have been considered to be lacking in immunity against rubella despite history to the contrary. This example of a long-term, circannual rhythm in an immunologic assay supports previous suggestions that immunity cycles over the seasons. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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