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| Titel: |
Infection of broiler chicks (Gallus domesticus) with human intestinal spirochaetes |
| Auteur: |
Dwars, R. M. Davelaar, F. G. Smit, H. F. |
| Verschenen in: |
Avian pathology |
| Paginering: | Jaargang 21 (1992) nr. 4 pagina's 559-568 |
| Jaar: |
1992-12 |
| Inhoud: |
One-day-old broiler chicks were infected orally with spirochaetes isolated from cases of intestinal disorder in humans. Three different isolates were studied in an experiment of 22 days duration. No signs of clinical disease were observed; the infection did not cause changes in the concentration of carotenoids or in the activity of alkaline phosphatase in the serum. Spirochaetes were shed in the caecal faeces. At autopsy, no lesions were seen in the intestinal tracts of the birds. Large numbers of spirochaetes were present in the caecum of 30 to 100% of the infected birds; in a few birds small numbers of spirochaetes were observed in scrapings from the mucosa of the small intestine. On histological examination massive colonisation of the caecal mucosa was observed. Spirochaetes of two isolates had invaded the caecal mucosa and for one of these, they were found between enterocytes, but not below the basement membrane. The other isolate had produced gap-like lesions, subepithelial accumulations of spirochaetes and focal erosion. No signs of an inflammatory reaction were observed. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 12 van 21 gevonden artikelen
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