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| Titel: |
Genomic selection |
| Auteur: |
Fernando, R. L. Habier, D. Stricker, C. Dekkers, J. C. M. Totir, L. R. |
| Verschenen in: |
Acta agriculturae Scandinavica. Section A, Animal science |
| Paginering: | Jaargang 57 (2007) nr. 4 pagina's 192-195 |
| Jaar: |
2007-12 |
| Inhoud: |
Computer simulation was used to examine the relationship between the number of loci included in the model and the accuracy of whole-genome methods for genetic evaluation. Random-regression BLUP (RR-BLUP) and Bayesian inference (Bayes-B) were compared with BLUP based on trait phenotypes and pedigree (TP-BLUP), where the genomic information consisted of genotypes at 110 or 2010 unlinked SNP loci. Of these loci, 10 were the actual trait loci. Accuracies for RR-BLUP were much higher than for TP-BLUP with 110 loci, but they were closer to TP-BLUP with 2010 loci. Accuracies with Bayes-B were close to 1 with 110 or with 2010 loci. Results for Bayes-B were also examined with a range of 3000 to 60 000 markers in linkage disequilibrium on 30 chromosomes. Increasing the number of markers did not lower the accuracy of Bayes-B. Thus, Bayes-B seems to be well suited for whole-genome analyses with large numbers of loci. This may not be the case for RR-BLUP. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 3 van 7 gevonden artikelen
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