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Details van artikel 5 van 9 gevonden artikelen
| Titel: |
Effect of Immunization against Somatostatin on Antibody Binding Capacity and Affinity, Hormone Concentrations, Performance and Carcass and Meat Quality in Young Friesian Bulls |
| Auteur: |
Ingvartsen, Klaus Lonne Sejrsen, Kristen Klastrup, Signe Foldager, John |
| Verschenen in: |
Acta agriculturae Scandinavica. Section A, Animal science |
| Paginering: | Jaargang 45 (1995) nr. 2 pagina's 116-123 |
| Jaar: |
1995-05-01 |
| Inhoud: |
Eight bull calves were immunized against somatostatin (SS) conjugated to human serum α-globulin (anti-SS), while another 8 were immunized against human serum α-globulin alone (placebo). All calves were tethered, individually fed concentrates ad libitum and slaughtered at an average live weight of 400 kg within each block. Only 5 of the 8 anti-SS calves formed significant amounts of antibodies, with an average binding capacity of 24-34 picomole SS per litre plasma and an antibody affinity (KD) of 0.20 ± 0.04 nM. No difference was found in daily gain (1454 vs. 1378 g, SEM = 71) although voluntary daily energy intake of concentrates was slightly higher (P = 0.17) in anti-SS calves (6.09 vs. 5.54 Scandinavian Feed Units, SEM = 0.27). Feed conversion was also higher (P = 0.08) in. anti-SS calves (4.20 vs. 4.01 SFU/kg gain, SEM = 0.7) and fat content (6.8 vs. 5.4 kg, SEM = 0.3) and amount of perirenal and mesenterial fat (8.45 vs. 6.26 kg, SEM = 0.44) was significantly increased (P < 0.01). Plasma levels of somatotropin and insulin were not altered by immunization. In contrast, insulin-like growth factor-I (IGF-I) was elevated in anti-SS calves following the 4th immunization (301 vs. 259 ng/ml, SEM = 13). The increased plasma IGF-I concentration is most likely a result of increased feed intake. However, a change in IGF-I secretion from liver cells owing to change in concentration of free SS is another possibility. The increased fat deposition also argues against involvement of ST. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 5 van 9 gevonden artikelen
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