QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model
Titel:
QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatment outcomes in an orthotopic breast cancer model
Auteur:
Kalra, Jessica Warburton, Corinna Fang, Karen Edwards, Lincoln Daynard, Tim Waterhouse, Dawn Dragowska, Wieslawa Sutherland, Brent W Dedhar, Shoukat Gelmon, Karen Bally, Marcel