Population PKPD Modeling of BACE1 Inhibitor-Induced Reduction in Aβ Levels In Vivo and Correlation to In Vitro Potency in Primary Cortical Neurons from Mouse and Guinea Pig
Titel:
Population PKPD Modeling of BACE1 Inhibitor-Induced Reduction in Aβ Levels In Vivo and Correlation to In Vitro Potency in Primary Cortical Neurons from Mouse and Guinea Pig
Auteur:
Janson, Juliette Eketjäll, Susanna Tunblad, Karin Jeppsson, Fredrik Berg, Stefan Von Niva, Camilla Radesäter, Ann-Cathrin Fälting, Johanna Visser, Sandra A. G.