Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors
Titel:
Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors
Auteur:
Arnold, Moriah R. Langelier, Marie-France Gartrell, Jessica Kirby, Ilsa T. Sanderson, Daniel J. Bejan, Daniel S. Å ileikytÄ—, Justina Sundalam, Sunil K. Nagarajan, Shanthi Marimuthu, Parthiban Duell, Anna K. Shelat, Anang A. Pascal, John M. Cohen, Michael S.