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Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo |
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Titel: |
Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo |
Auteur: |
Luo, Guoshun Li, Zhenbang Lin, Xin Li, Xinyu Chen, Yu Xi, Kun Xiao, Maoxu Wei, Hanlin Zhu, Lizhe Xiang, Hua |
Verschenen in: |
Acta pharmaceutica sinica B |
Paginering: |
Jaargang 11 () nr. 5 pagina's 1300-1314 |
Jaar: |
2021 |
Inhoud: |
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Uitgever: |
Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences |
Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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