Rational drug design, synthesis, and biological evaluation of novel chiral tetrahydronaphthalene-fused spirooxindole as MDM2-CDK4 dual inhibitor against glioblastoma
Titel:
Rational drug design, synthesis, and biological evaluation of novel chiral tetrahydronaphthalene-fused spirooxindole as MDM2-CDK4 dual inhibitor against glioblastoma
Auteur:
Wang, Biao Peng, Fu Huang, Wei Zhou, Jin Zhang, Nan Sheng, Jia Haruehanroengra, Phensinee He, Gu Han, Bo
Verschenen in:
Acta pharmaceutica sinica B
Paginering:
Jaargang 10 () nr. 8 pagina's 1492-1510
Jaar:
2020
Inhoud:
Uitgever:
Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences