Molecular modelling showed optimal fit between TSR5 in trimeric properdin and C345C in the C3b moiety for stabilization of the alternative convertase, whereas binding to molecular patterns in myeloperoxidase, endothelial cells and Neisseria meningitides was indirectly mediated by initial C3 activation
Title:
Molecular modelling showed optimal fit between TSR5 in trimeric properdin and C345C in the C3b moiety for stabilization of the alternative convertase, whereas binding to molecular patterns in myeloperoxidase, endothelial cells and Neisseria meningitides was indirectly mediated by initial C3 activation
Author:
Harboe, Morten Johnson, Christina Nymo, Stig Ekholt, Karin Schjalm, Camilla Lindstad, Julie K. Pharo, Anne Hellerud, Bernt C. Ekdahl, Kristina N. Mollnes, Tom E. Nilsson, Per H.