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  Cathodal stimulation of human MT+ leads to elevated fMRI signal: A tDCS-fMRI study
 
 
Titel: Cathodal stimulation of human MT+ leads to elevated fMRI signal: A tDCS-fMRI study
Auteur: Antal, Andrea
Kovács, Gyula
Chaieb, Leila
Cziraki, Csaba
Paulus, Walter
Greenlee, Mark W.
Verschenen in: Restorative neurology and neuroscience
Paginering: Jaargang 30 (2012) nr. 3 pagina's 255-263
Jaar: 2012-04-04
Inhoud: Purpose: Transcranial direct current stimulation (tDCS) was reintroduced about a decade ago as a tool for inducing long-lasting changes in cortical excitability. Recently it has been shown that both motor and cognitive functions can be influenced by tDCS. Here, we tested the effect of tDCS on the blood-oxygen level dependent (BOLD) signal evoked by coherent visual motion using functional magnetic resonance imaging (fMRI). Methods: The subjects underwent 10 min of cathodal and sham tDCS, applied over the right MT+. Following stimulation, random dot kinomatograms (RDK) with different percentages (10%, 30%, 50%) of coherently moving dots were presented. Results: All motion stimuli activated MT+ in both stimulation conditions. However, cathodal stimulation led to an increase in fMRI signal in MT+ when compared to sham stimulation. This effect did not depend on the coherence level of the visual stimulus. Conclusions: Here, we show for the first time, that cathodal tDCS stimulation leads to elevated fMRI signal in the human visual cortex.
Uitgever: IOS Press
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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