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  Repeated sessions of noninvasive brain DC stimulation is associated with motor function improvement in stroke patients
 
 
Titel: Repeated sessions of noninvasive brain DC stimulation is associated with motor function improvement in stroke patients
Auteur: Boggio, Paulo S.
Nunes, Alice
Rigonatti, Sergio P.
Nitsche, Michael A.
Pascual-Leone, Alvaro
Fregni, Felipe
Verschenen in: Restorative neurology and neuroscience
Paginering: Jaargang 25 (2007) nr. 2 pagina's 123-129
Jaar: 2007-08-22
Inhoud: Purpose: Recent evidence has suggested that a simple technique of noninvasive brain stimulation – transcranial direct current stimulation (tDCS) – is associated with a significant motor function improvement in stroke patients. Methods: We tested the motor performance improvement in stroke patients following 4 weekly sessions of sham, anodal- and cathodal tDCS (experiment 1) and the effects of 5 consecutive daily sessions of cathodal tDCS (experiment 2). A blinded rater evaluated motor function using the Jebsen-Taylor Hand Function Test. Results: There was a significant main effect of stimulation condition (p=0.009) in experiment 1. Furthermore there was a significant motor function improvement after either cathodal tDCS of the unaffected hemisphere (p=0.016) or anodal tDCS of the affected hemisphere (p=0.046) when compared to sham tDCS. There was no cumulative effect associated with weekly sessions of tDCS, however consecutive daily sessions of tDCS (experiment 2) were associated with a significant effect on time (p< 0.0001) that lasted for 2 weeks after treatment. Conclusions: The findings of our study support previous research showing that tDCS is significantly associated with motor function improvement in stroke patients; and support that consecutive daily sessions of tDCS might increase its behavioral effects. Because the technique of tDCS is simple, safe and non-expensive; our findings support further research on the use of this technique for the rehabilitation of patients with stroke.
Uitgever: IOS Press
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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