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| Titel: |
Generation of Nanoparticles of Lubricating Motor Oil for Inhalation Studies |
| Auteur: |
Fujitani, Yuji Ideno, Yoshihiro Fushimi, Akihiro Tanabe, Kiyoshi Kobayashi, Shinji Kobayashi, Takahiro |
| Verschenen in: |
Aerosol science and technology |
| Paginering: | Jaargang 41 (2007) nr. 1 pagina's 14-23 |
| Jaar: |
2007-01 |
| Inhoud: |
Recent studies suggest that most 20-30 nm nanoparticles measured at roadsides are composed mainly of organic carbon derived from lubricating motor oil. Therefore, a simple particle generation system has been developed for controlled production of 20-30 nm nanoparticles of lubricating motor oil for inhalation toxicology studies by means of vapor condensation without addition of nuclei. Quasi-monodisperse particles with a modal diameter located at 20 nm and total number concentrations above 106 cm-3 were generated. Ten 2-h particle generation reproducibility tests were conducted, in which stability and repeatability of particle size and total number concentration were good. Organic carbon is a major component of oil particles, and organic analysis showed that the compositions of oil particles were not subjected to distillation of organic compounds through evaporation to condensation. Using the nose-exposure system connected to the particle generation system, toxicity of 20-nm particle organic compounds of lubricating motor oil can be assessed by inhalation studies of experimental animals. |
| Uitgever: |
Taylor & Francis |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 4 van 9 gevonden artikelen
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