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  Ultrafine Particle Deposition in a Human Tracheobronchial Cast
 
 
Titel: Ultrafine Particle Deposition in a Human Tracheobronchial Cast
Auteur: Cohen, Beverly S.
Sussman, Robert G.
Lippmann, Morton
Verschenen in: Aerosol science and technology
Paginering: Jaargang 12 (1990) nr. 4 pagina's 1082-1091
Jaar: 1990
Inhoud: The deposition of 0.20, 0.15, and 0.04 μm diameter particles was measured in a human central airway cast using a variable larynx with cyclic inspiratory flow. Data were compared with theoretical predictions for deposition from laminar flow for the first seven airway generations. With the exception of tracheal deposition, which on average exceeded predictions by a factor of 9, the measured deposition was about twice that predicted. The enhanced deposition is attributable to secondary swirling flows. Less enhancement is observed at higher inspiratory flow rates as turbulence increases. The surface density of particles deposited at bifurcations was approximately 20% greater than along the airway lengths. This increased deposition at bifurcations should be considered when calculating tissue dose for particles which act before the initial deposit is removed by clearance processes.
Uitgever: Taylor & Francis
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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