In the mid 1960s, an epidemic of rubella, also known as German measles, swept across the country. Women who contracted rubella during the first trimester of pregnancy gave birth to babies with an array of problems including deafness, blindness, heart problems, and developmental disabilities. Of the thousands of children estimated to have been born with congenital rubella syndrome (CRS) during that time, many were born deaf-blind and with cognitive delays. As these children entered their adult years, there were reports that some were developing additional medical conditions. This article summarizes the results of a national survey conducted by the Helen Keller National Center for Deaf-Blind Youths and Adults from 1989 to 1991. The goal of the survey was to determine the nature, scope and severity of late onset symptoms in those who are deaf-blind due to CRS. Results indicated that in addition to higher than expected incidences of glaucoma and diabetes, there were reports of hypo- and hyperthyroidism, hormone imbalances, premature aging, and esophageal and gastrointestinal problems.