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| Titel: |
The effect of interferon beta 1B on bone mineral density in multiple sclerosis patients |
| Auteur: |
Varoglu, Asuman Orhan Varoglu, Erhan Bayraktar, Rezzan Aygul, Recep Ulvi, Hizir Yildirim, Kadir |
| Verschenen in: |
Journal of back and musculoskeletal rehabilitation |
| Paginering: | Jaargang 23 (2010) nr. 1 pagina's 25-29 |
| Jaar: |
2010-03-15 |
| Inhoud: |
Objective: Osteoporosis is a secondary problem in multiple sclerosis (MS) patients. There have been only a few reports about the effect of interferon beta (IFNB) 1b on bone mineral density (BMD). We aimed to determine bone mass in patients using IFNB 1b. Methods: We enrolled 17 patients taking IFNB 1b (group I), 15~patients not taking IFNB (group II). We measured the BMD and T scores values and the patients were distinguished as normal, osteopenia and osteoporosis. Results: In the lumbar spine, there was no difference between groups I and II (p=0.3). In the left femur, no significant difference was detected between groups I and II (p=1). There was an inverse correlation between the BMD at the both regions and the Expanded Disability Status Scale score (r= −0.39, p=0.03; r=−0.52, p=0.002, respectively). Conclusion: IFNB 1b may be used safely in MS patients, even in those undergoing pulse steroid therapies, because IFNB 1b has no effect on BMD. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 7 van 7 gevonden artikelen
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