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                                       Details van artikel 9 van 11 gevonden artikelen
 
 
  Modification of the cell adhesion and hydrophilic characteristics of poly(ether-ether-ketone) by 172-nm Xenon excimer radiation
 
 
Titel: Modification of the cell adhesion and hydrophilic characteristics of poly(ether-ether-ketone) by 172-nm Xenon excimer radiation
Auteur: Okada, Yukimasa
Furumatsu, Takayuki
Miyazawa, Shinichi
Fujii, Masataka
Takahashi, Hiroyuki
Kimura, Hiroomi
Ozaki, Toshifumi
Abe, Nobuhiro
Verschenen in: Bio-medical materials and engineering
Paginering: Jaargang 25 (2015) nr. 2 pagina's 169-175
Jaar: 2015-03-26
Inhoud: BACKGROUND: Poly-ether-ether-ketone (PEEK) has biomechanical and chemical properties that are excellent for biomedical applications; however, PEEK adhesion to bone or chondral tissue proceeds slowly due to poor hydrophilicity and other surface characteristics. OBJECTIVE: We investigated the structural change, hydrophilicity, and cytocompatibility of a PEEK surface after 172-nm xenon excimer UV-irradiation. METHODS: The surface characteristics before and after irradiation were evaluated by contact angle and ATR-FTIR measurements. Mouse osteoblast-like cells (MC3T3-E1) were cultured on PEEK plates and collected after 6, 12 and 24 h for cell adhesion analysis by crystal violet staining (CVS) and scanning electron microscopy (SEM). RESULTS: UV-irradiation improved PEEK surface hydrophilicity, as indicated by a significant drop in water contact angle (p<0.05). Irradiated PEEK showed additional peaks around 3370 cm−1 and 1720 cm−1, highlighting the generation of hydroxyl and carbonyl groups. CVS and SEM revealed improved adhesion to the PEEK surface after UV-irradiation. CONCLUSION: Our results suggest that 172-nm UV-irradiated PEEK may be used in biomedical applications that require good cell adhesion.
Uitgever: IOS Press
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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