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| Titel: |
Preparation of size-controlled silver nanoparticles and chitosan-based composites and their anti-microbial activities |
| Auteur: |
Nguyen, Vinh Quang Ishihara, Masayuki Mori, Yasutaka Nakamura, Shingo Kishimoto, Satoko Fujita, Masanori Hattori, Hidemi Kanatani, Yasuhiro Ono, Takeshi Miyahira, Yasushi Matsui, Takemi |
| Verschenen in: |
Bio-medical materials and engineering |
| Paginering: | Jaargang 23 (2013) nr. 6 pagina's 473-483 |
| Jaar: |
2013-10-28 |
| Inhoud: |
We previously reported a simple method for the preparation of size-controlled spherical silver nanoparticles (Ag NPs) generated by autoclaving a mixture of silver-containing glass powder and glucose. The particle size is regulated by the glucose concentration, with concentrations of 0.25, 1.0 and 4.0 wt% glucose providing small (3.48±1.83 nm in diameter), medium (6.53±1.78 nm) and large (12.9±2.5 nm) particles, respectively. In this study, Ag NP/chitosan composites were synthesized by mixing each of these three Ag NP suspensions with a 75% deacetylated (DAc) chitosan suspension (pH 5.0) at room temperature. The Ag NPs were homogeneously dispersed and stably embedded in the chitosan matrices. The Ag NP/chitosan composites were obtained as yellow or brown flocs. It was estimated that approximately 60, 120 and 360 μg of the small, medium and large Ag NPs, respectively, were maximally embedded in 1 mg of chitosan. The bactericidal and anti-fungal activities of the Ag NP/chitosan composites increased as the amount of Ag NPs in the chitosan matrix increased. Furthermore, smaller Ag NPs (per weight) in the chitosan composites provided higher bactericidal and anti-fungal activities. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 12 van 12 gevonden artikelen
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