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| Titel: |
Injectable biphasic calcium phosphate bioceramic: The HYDROS® concept |
| Auteur: |
Baroth, Serge Bourges, Xavier Goyenvalle, Eric Aguado, Eric Daculsi, Guy |
| Verschenen in: |
Bio-medical materials and engineering |
| Paginering: | Jaargang 19 (2009) nr. 1 pagina's 71-76 |
| Jaar: |
2009-05-20 |
| Inhoud: |
A new biphasic calcium phosphate ceramic material has been developed in our laboratory. It is composed of 60% of hydroxyapatite and 40% of β-tricalcium phosphate, based on three granulometries (submicron, round microporous 80–200 μm and macro microporous 0.5–1 mm particles) and hydrated with water leading the formation of a putty filler for bone repair. Biocompatibility and osteogenicity were tested by filling femoral epiphyses critical size bone defect and lumbar muscles in rabbit. After 3, 6 and 12 weeks of implantation, explants were treated for histology. Results revealed the biocompatibility of the material and intensive resorption of the submicron particle fraction followed by important bone ingrowth whereas osteoconduction was provided by the larger particles. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 6 van 10 gevonden artikelen
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