|
| << vorige | volgende >> |
Tijdschrift beschrijving
Alle jaargangen van het bijbehorende tijdschrift
Alle afleveringen van het bijbehorende jaargang
Alle artikelen van de bijbehorende aflevering
Details van artikel 14 van 29 gevonden artikelen
| Titel: |
In vivo rat knee cartilage volume measurement using quantitative high resolution MRI (7 T): Feasibility and reproducibility |
| Auteur: |
Goebel, Jean-Christophe Bolbos, Radu Pinzano, Astrid Schaeffer, Mathilde Rengle, Adrian Galois, Laurent Etienne, Stéphanie Netter, Patrick Loeuille, Damien Beuf, Olivier Gillet, Pierre |
| Verschenen in: |
Bio-medical materials and engineering |
| Paginering: | Jaargang 18 (2008) nr. 4-5 pagina's 247-252 |
| Jaar: |
2008-12-08 |
| Inhoud: |
Objectives: to assess reliability and reproducibility of quantitative MRI (7 T) in assessing rat femoro-tibial cartilage volume. Methods: 5 healthy rat knees were scanned in vivo using a 7 T experimental imager. Sagittal high resolution 3D Gradient Echo with fat suppression sequences were performed with a dedicated home-made 2-elements array coil. 3D MRI sets were used to perform manual segmentation of the 3 cartilage compartments (femoral groove, medial and lateral tibial plateaus) by using a tactile screen. To evaluate inter- and intra-observer reproducibilities, the segmentation procedure was done blindly by two trained observers. One observer repeated the operation twice, with a period of 10 months between both readings. Results: the mean duration to manually segment all the slices covering the cartilaginous joint was 4 hours. On the one hand, the inter-observer root mean square of coefficients of variation was 9.1%, 6.2%, 9.6% for the femoral, medial and lateral tibial compartments respectively. On the other hand, the intra-observer reproducibility was 2.1%, 3.2%, 2.5% for these cartilage compartments cited above. Conclusion: the image quality obtained at 7 Teslas with our dedicated coil allowed segmentation of the cartilage compartments with good reproducibility. This study demonstrated that MRI is a useful technology to provide a non-invasive and reliable assessment of rat knee cartilage volume. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 14 van 29 gevonden artikelen
| << vorige | volgende >> |