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Journal description
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Details for article 22 of 23 found articles
| Title: |
Ultrathin polymer monolayers for promotion of cell growth on bioprosthetic materials - Evolution of a new concept to improve long term performance of biologic heart vales |
| Author: |
Manfred Dahm Jürgen Rühe Bernd Berchthold Diethard Prüfer Oswald Prucker Bung-Jun Chang Anja Wallrath Hellmut Oelert |
| Appeared in: |
Bio-medical materials and engineering |
| Paging: | Volume 14 (2004) nr. 4 pages 419-425 |
| Year: |
2004-12-27 |
| Contents: |
Reoperation of aldehyde tanned bioprotheses due to calcific degeneration remains their major drawback. Based on experiments studying mechanisms and factors that influence the time phase, extent and progression of calcification and evaluating the efficiency of anticalcification treatments and the effects of surface seeding with vital cells a new concept to avoid calcification emerged: masking aldehyde-residues with a covalently bound polymer that supports surface cell seeding. Different covalently bound polymers were tested for their suitability to grow cells. Dense cell growth was achieved on some polymers but without correlation to physico-chemical properties. Ultrathin coating of biological materials appears a promising approach to achieve lining with vital cells. |
| Publisher: |
IOS Press |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 22 of 23 found articles
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