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Details for article 9 of 9 found articles
| Title: |
Three-dimensional model of bone marrow stromal cell culture |
| Author: |
Maciej Januszewski Zbigniew Dąbrowski Maria Adamus Tadeusz Niedźwiedzki |
| Appeared in: |
Bio-medical materials and engineering |
| Paging: | Volume 13 (2003) nr. 1 pages 1-9 |
| Year: |
2003-03-27 |
| Contents: |
In a hematopoietic microenvironment in vivo, spatial organisation of hematopoiesis is possible due to the existence of a three-dimensional framework, the main part of which is formed by a branching population of stromal cells. Most of the previous in vitro studies, concerning long-term bone marrow cultures, were based on a previously prepared, flat adherent layer of stromal cells. There are only few reports concerning the three-dimensional growth pattern of the bone marrow stroma. In the present study we used a new three-dimensional model of the stromal cell culture. The framework for the cultured stromal cells was a structure of a nonliving trabecular bone (Unilab Surgibone). After a period of about four weeks the stromal cells created a spatial network which filled the intertrabecular spaces of the spongy bone. |
| Publisher: |
IOS Press |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 9 of 9 found articles
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