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                                       Details for article 23 of 33 found articles
 
 
  Osteogenesis mechanism based on kinetic theory
 
 
Title: Osteogenesis mechanism based on kinetic theory
Author: A. Toshimitsu Yokobori
Appeared in: Bio-medical materials and engineering
Paging: Volume 8 (2001) nr. 5-6 pages 253-257
Year: 2001-04-01
Contents: In our earlier studies, we considered osteogenesis to be a nucleation mechanism accompanied by preliminary diffusion and showed the optimum mechanical conditions for promoting this ionic diffusion. In this study, we performed an analysis of the nucleation mechanism of hydroxyapatite (HA) in areas with a high concentration of transported Ca and PO<inf>4</inf> ions in the pore region along the collagen alignment. We derived the equation of the HA nucleation rate as a function of hydrostatic tensile stress, \sigma _{\rm P} and surface energy change (\gamma -\lambda ), where \gamma is the surface energy of the HA particle and \lambda is the decreasing factor of \gamma during HA nucleation. \lambda is thus related to the effect of chemical and electric stimulations. Finally, we formulated a unified equation of the nucleation rate of HA, which consists of ionic diffussion and HA nucleation processes.
Publisher: IOS Press
Source file: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details for article 23 of 33 found articles
 
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