The peripheral benzodiazepine receptor ligand PK11195 binds with high affinity to the acute phase reactant α1-acid glycoprotein: implications for the use of the ligand as a CNS inflammatory marker 1 1 List of abbreviations: AD, Alzheimer’s disease; AGP, α1-acid glycoprotein; APO, apolipoprotein A1; BBB, blood brain barrier; HSA, human serum albumin; MS, multiple sclerosis; PBR, peripheral benzodiazepine receptor; PBS, phosphate buffered saline; PET, positron emission tomography; PK11195, 1-[2-chlorophenyl]-N-methyl-N-[1-methyl-propyl]-3-isoquinoline carboxamide
Titel:
The peripheral benzodiazepine receptor ligand PK11195 binds with high affinity to the acute phase reactant α1-acid glycoprotein: implications for the use of the ligand as a CNS inflammatory marker 1 1 List of abbreviations: AD, Alzheimer’s disease; AGP, α1-acid glycoprotein; APO, apolipoprotein A1; BBB, blood brain barrier; HSA, human serum albumin; MS, multiple sclerosis; PBR, peripheral benzodiazepine receptor; PBS, phosphate buffered saline; PET, positron emission tomography; PK11195, 1-[2-chlorophenyl]-N-methyl-N-[1-methyl-propyl]-3-isoquinoline carboxamide
Auteur:
Lockhart, Andrew Davis, Bill Matthews, Julian C. Rahmoune, Hassan Hong, Guizhu Gee, Antony Earnshaw, David Brown, John