Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer
Title:
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer
Author:
Penning, Thomas D. Zhu, Gui-Dong Gandhi, Viraj B. Gong, Jianchun Thomas, Sheela Lubisch, Wilfried Grandel, Roland Wernet, Wolfgang Park, Chang H. Fry, Elizabeth H. Liu, Xuesong Shi, Yan Klinghofer, Vered Johnson, Eric F. Donawho, Cherrie K. Frost, David J. Bontcheva-Diaz, Velitchka Bouska, Jennifer J. Olson, Amanda M. Marsh, Kennan C. Luo, Yan Rosenberg, Saul H. Giranda, Vincent L.