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                                       Details van artikel 8 van 11 gevonden artikelen
 
 
  Influence of sampling practices on the appearance of DNA image histograms of prostate cells in FNAB samples
 
 
Titel: Influence of sampling practices on the appearance of DNA image histograms of prostate cells in FNAB samples
Auteur: Abdelbaset Buhmeida
Teijo Kuopio
Yrjö Collan
Verschenen in: Analytical cellular pathology
Paginering: Jaargang 18 (2001) nr. 2 pagina's 95-102
Jaar: 2001-04-01
Inhoud: Twenty-one fine needle aspiration biopsies (FNAB) of the prostate, diagnostically classified as definitely malignant, were studied. The Papanicolaou or H&E stained samples were destained and then stained for DNA with the Feulgen reaction. DNA cytometry was applied after different sampling rules. The histograms varied according to the sampling rule applied. Because free cells between cell groups were easier to measure than cells in the cell groups, two sampling rules were tested in all samples: (i) cells in the cell groups were measured, and (ii) free cells between cell groups were measured. Abnormal histograms were more common after the sampling rule based on free cells, suggesting that abnormal patterns are best revealed through the free cells in these samples. The conclusions were independent of the applied histogram interpretation method.
Uitgever: IOS Press
Bronbestand: Elektronische Wetenschappelijke Tijdschriften
 
 

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