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                                       Details for article 5 of 12 found articles
 
 
  Detection of human papillomavirus type 2 related sequence in oral papilloma
 
 
Title: Detection of human papillomavirus type 2 related sequence in oral papilloma
Author: Taihei Yamaguchi
Masanobu Shindoh
Akira Amemiya
Nobuo Inoue
Masaaki Kawamura
Hiroshi Sakaoka
Masakazu Inoue
Kei Fujinaga
Appeared in: Analytical cellular pathology
Paging: Volume 16 (2001) nr. 3 pages 125-130
Year: 2001-04-01
Contents: Oral papilloma is a benign tumourous lesion. Part of this lesion is associated with human papillomavirus (HPV) infection. We analysed the genetical and histopathological evidence for HPV type 2 infection in three oral papillomas. Southern blot hybridization showed HPV 2a sequence in one lesion. Cells of the positive specimen appeared to contain high copy numbers of the viral DNA in an episomal state. In situ staining demonstrated virus capsid antigen in koilocytotic cells and surrounding cells in the hyperplastic epithelial layer. Two other specimens contained no HPV sequences by labeled probe of full length linear HPVs 2a, 6b, 11, 16, 18, 31 and 33 DNA under low stringency hybridization conditions. These results showed the possibility that HPV 2 plays a role in oral papilloma.
Publisher: IOS Press
Source file: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details for article 5 of 12 found articles
 
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