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                                       Details for article 3 of 13 found articles
 
 
  Atypical antipsychotic agents for the schizophrenia prodrome: Not a clear first choice
 
 
Title: Atypical antipsychotic agents for the schizophrenia prodrome: Not a clear first choice
Author: Kruszewski, Stefan P.
Paczynski, Richard P.
Appeared in: International journal of risk & safety in medicine
Paging: Volume 20 (2008) nr. 1-2 pages 37-44
Year: 2008-04-11
Contents: Pharmacologic intervention at the earliest stages of suspected psychotic illness is an intuitively appealing concept and a logical extension of the current approach to many other diseases of the central nervous system. Atypical antipsychotic agents (ATAPs) seem to be a reasonable choice for early intervention because existing pre-clinical data suggest that they have pharmacologic properties which might confer ‘neuroprotection’. However, a critical analysis of the results of structured clinical investigations which have explored the use of ATAPs for new-onset psychotic symptoms raises safety concerns and does not support pre-medication in this setting as a preventive strategy. Caution in current practice is therefore appropriate, underscoring the need for much additional clinical research.
Publisher: IOS Press
Source file: Elektronische Wetenschappelijke Tijdschriften
 
 

                             Details for article 3 of 13 found articles
 
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