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| Titel: |
Safety and use of medicines in mental health at the psychiatric hospital of the Republic of Tatarstan (Russia) |
| Auteur: |
Ziganshina, Lilia E. Kuchaeva, Alexandra V. Vedernikova, Olga O. Gatin, Foat F. Ziganshin, Airat U. |
| Verschenen in: |
International journal of risk & safety in medicine |
| Paginering: | Jaargang 18 (2006) nr. 2 pagina's 83-90 |
| Jaar: |
2006-06-23 |
| Inhoud: |
Neuroleptics' safety and use survey was conducted with the aim to develop a drug use monitoring system at a regional psychiatric hospital as an efficient tool of improving use of anti-psychotics. 7080 Side-effects report slips included into the regular medical charts for the period of 4 years (2000-2003) and 385 medical charts for the twelve months of the year 1960 were studied. The total daily neuroleptic load was calculated with the help of Chlorpromazine equivalents and ATC/DDD methodology. It was confirmed that clinical form of paranoid schizophrenia, age and gender contribute to the increased susceptibility of patients to development of movement disorders: women, patients over 60 years of age and youngsters, and patients with cerebral-organic deficiency being the most vulnerable. The most common patterns of inadequate prescribing practice included needless overuse of neuroleptics; combination treatment of highly dosed neuroleptics; simultaneous prescribing of anticholinergics (trihexyphenidyl) with neuroleptics; clozapine use only as a sedative component. Pharmacovigilance system proved to be an effective instrument in monitoring but not necessarily improving prescribing practices. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 4 van 8 gevonden artikelen
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