New 8-hydroxyquinoline and catecholate iron chelators: influence of their partition coefficient on their biological activity 1 1 Abbreviations: Kpart, partition coeffient; DFO, desferrioxamine B; TRX, O-Trensox; pFe = −log[Fe3+ aq] at pH 7.4 with [Ligand] = 10 μM and [Fe] = 1 μM; LDH, lactate dehydrogenase; and PBS, phosphate-buffered saline.
Titel:
New 8-hydroxyquinoline and catecholate iron chelators: influence of their partition coefficient on their biological activity 1 1 Abbreviations: Kpart, partition coeffient; DFO, desferrioxamine B; TRX, O-Trensox; pFe = −log[Fe3+ aq] at pH 7.4 with [Ligand] = 10 μM and [Fe] = 1 μM; LDH, lactate dehydrogenase; and PBS, phosphate-buffered saline.
Auteur:
Henry, Christophe Rakba, Nafissa Imbert, Daniel Thomas, Fabrice Baret, Paul Serratrice, Guy Gaude, Didier Pierre, Jean-Louis Ward, Roberta J. Crichton, Robert R. Lescoat, Gerard