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Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism
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Abbreviations: ACT D, actinomycine D; CHX, cycloheximide; COX, cyclooxygenase; CuDips, Cu(II) (3,5-diisopropylsalicylate)2; DMSO, dimethyl sulfoxide; D-NMMA, Nω-monomethyl-D-arginine; FCS, heat-inactivated fetal calf serum; H2O2, hydrogen peroxide; IL-1β, interleukin-1β; L-Arg, L-arginine; L-NMMA, Nω-monomethyl-L-arginine; NO, Nitric oxide; NO2
−, nitrites; NOS, nitric oxide synthase; NSAID, non steroidal anti-inflammatory drug; PGE2, prostaglandin E2; RT-PCR, reverse transcription-polymerase chain reaction; SIN-1, 3-morpholinosydnonimine; SMT, S-methylisothiourea; SOD, superoxide dismutase. |
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Titel: |
Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism
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1
Abbreviations: ACT D, actinomycine D; CHX, cycloheximide; COX, cyclooxygenase; CuDips, Cu(II) (3,5-diisopropylsalicylate)2; DMSO, dimethyl sulfoxide; D-NMMA, Nω-monomethyl-D-arginine; FCS, heat-inactivated fetal calf serum; H2O2, hydrogen peroxide; IL-1β, interleukin-1β; L-Arg, L-arginine; L-NMMA, Nω-monomethyl-L-arginine; NO, Nitric oxide; NO2
−, nitrites; NOS, nitric oxide synthase; NSAID, non steroidal anti-inflammatory drug; PGE2, prostaglandin E2; RT-PCR, reverse transcription-polymerase chain reaction; SIN-1, 3-morpholinosydnonimine; SMT, S-methylisothiourea; SOD, superoxide dismutase. |
Auteur: |
Nédélec, Emmanuelle Abid, Amr Cipolletta, Christine Presle, Nathalie Terlain, Bernard Netter, Patrick Jouzeau, Jean-Yves |
Verschenen in: |
Biochemical pharmacology |
Paginering: |
Jaargang 61 (2001) nr. 8 pagina's 14 p. |
Jaar: |
2001 |
Inhoud: |
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Uitgever: |
Elsevier Science Inc. |
Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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