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Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells 2 2 Abbreviations: AhR, aryl hydrocarbon receptor; CAT, chloramphenicol acetyl transferase; CYP1A1, cytochrome P450 1A1; FBS, fetal bovine serum; GADD, growth arrest and DNA damage; GRP78, 78-kD glucose-regulated protein; GST, glutathione S-transferase; HMTII, human metallothionein II; HSP, heat shock protein; 3-MC, 3-methylcholanthrene; NF-κBRE, nuclear factor of κ enhancer responsive element; RARE, retinoid acid responsive element; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDF, 2,3,7,8-tetrachlorodibenzofuran; UDS, unscheduled DNA synthesis; and XRE, xenobiotic responsive element. |
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Titel: |
Induction of cytochrome P450 1A1 gene expression, oxidative stress, and genotoxicity by carbaryl and thiabendazole in transfected human HepG2 and lymphoblastoid cells 2 2 Abbreviations: AhR, aryl hydrocarbon receptor; CAT, chloramphenicol acetyl transferase; CYP1A1, cytochrome P450 1A1; FBS, fetal bovine serum; GADD, growth arrest and DNA damage; GRP78, 78-kD glucose-regulated protein; GST, glutathione S-transferase; HMTII, human metallothionein II; HSP, heat shock protein; 3-MC, 3-methylcholanthrene; NF-κBRE, nuclear factor of κ enhancer responsive element; RARE, retinoid acid responsive element; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDF, 2,3,7,8-tetrachlorodibenzofuran; UDS, unscheduled DNA synthesis; and XRE, xenobiotic responsive element. |
Auteur: |
Delescluse, Chantal Ledirac, Nathalie Li, Rouya Piechocki, Marie P Hines, Ronald N Gidrol, Xavier Rahmani, Roger |
Verschenen in: |
Biochemical pharmacology |
Paginering: |
Jaargang 61 (2001) nr. 4 pagina's 9 p. |
Jaar: |
2001 |
Inhoud: |
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Uitgever: |
Elsevier Science Inc. |
Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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