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Oxidative activation of indole-3-acetic acids to cytotoxic species— a potential new role for plant auxins in cancer therapy 1 1 Abbreviations: IAA, indole-3-acetic acid; HRP, horseradish peroxidase; TBA, thiobarbituric acid; MPO, myeloperoxidase; MOI, 3-methylene-2-oxindole; BSO, buthionine sulphoximine; GSH, glutathione; CEA, carcinoembryonic antigen; ADEPT, antibody directed enzyme prodrug therapy; PDEPT, polymer directed enzyme prodrug therapy; GDEPT, gene directed enzyme prodrug therapy; and PEG, polyethylene glycol. |
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Titel: |
Oxidative activation of indole-3-acetic acids to cytotoxic species— a potential new role for plant auxins in cancer therapy 1 1 Abbreviations: IAA, indole-3-acetic acid; HRP, horseradish peroxidase; TBA, thiobarbituric acid; MPO, myeloperoxidase; MOI, 3-methylene-2-oxindole; BSO, buthionine sulphoximine; GSH, glutathione; CEA, carcinoembryonic antigen; ADEPT, antibody directed enzyme prodrug therapy; PDEPT, polymer directed enzyme prodrug therapy; GDEPT, gene directed enzyme prodrug therapy; and PEG, polyethylene glycol. |
Auteur: |
Folkes, Lisa K. Wardman, Peter |
Verschenen in: |
Biochemical pharmacology |
Paginering: |
Jaargang 61 (2001) nr. 2 pagina's 8 p. |
Jaar: |
2001 |
Inhoud: |
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Uitgever: |
Elsevier Science Inc. |
Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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