Involvement of A3 receptors in the potentiation by adenosine of the inhibitory effect of theophylline on human eosinophil degranulation: possible novel mechanism of the anti-inflammatory action of theophylline 1 1 Abbreviations: C5a, complement fragment 5a; ECP, eosinophil cationic protein; EDN, eosinophil-derived neurotoxin; EPO, eosinophil peroxidase; OPD, O-phenylenediamine; CGS 21680, 2-[[2-[4-(2-carboxyethyl)phenyl]ethyl]amino]-N-ethylcarboxamidoadenosine; CPA, N-cyclopentyladenosine; DMPX, 3,7-dimethyl-1-propargylxanthine; DPCPX, 1,3-dipropyly-8-cyclo-pentylxanthine; IB-MECA, N 6-(3-iodobenzyl)-5′-N-methylcarbamoyladen-osine; MBP, major basic protein; MRS1220, 9-chloro-2-(2-furyl)-5-phenyl-actylamino[1,2,4]triazolo[1,5-c]quinazoline; PDE, phosphodiesterase; cAMP, adenosine 3′,5′-cyclic monophosphate.
Titel:
Involvement of A3 receptors in the potentiation by adenosine of the inhibitory effect of theophylline on human eosinophil degranulation: possible novel mechanism of the anti-inflammatory action of theophylline 1 1 Abbreviations: C5a, complement fragment 5a; ECP, eosinophil cationic protein; EDN, eosinophil-derived neurotoxin; EPO, eosinophil peroxidase; OPD, O-phenylenediamine; CGS 21680, 2-[[2-[4-(2-carboxyethyl)phenyl]ethyl]amino]-N-ethylcarboxamidoadenosine; CPA, N-cyclopentyladenosine; DMPX, 3,7-dimethyl-1-propargylxanthine; DPCPX, 1,3-dipropyly-8-cyclo-pentylxanthine; IB-MECA, N 6-(3-iodobenzyl)-5′-N-methylcarbamoyladen-osine; MBP, major basic protein; MRS1220, 9-chloro-2-(2-furyl)-5-phenyl-actylamino[1,2,4]triazolo[1,5-c]quinazoline; PDE, phosphodiesterase; cAMP, adenosine 3′,5′-cyclic monophosphate.
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