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Effects of epidermal growth factor on CYP inducibility by xenobiotics, DNA replication, and caspase activations in collagen I gel sandwich cultures of rat hepatocytes 1 1 Abbreviations: BrdU, 5-bromo 2′-deoxyuridine; Cdk 1, Cyclin dependent kinase 1; CYP, cytochrome P450; DEVD-AMC, N-acetyl-Asp-Glu-Val-Asp-aminomethylcoumarin; EGF, epidermal growth factor; EROD, ethoxyresorufin O-deethylase; 3-MC, 3-methylcholantrene; β-NF, β-naphtoflavone; PB, phenobarbital; and PROD, pentoxyresorufin O-depentylase. |
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Titel: |
Effects of epidermal growth factor on CYP inducibility by xenobiotics, DNA replication, and caspase activations in collagen I gel sandwich cultures of rat hepatocytes 1 1 Abbreviations: BrdU, 5-bromo 2′-deoxyuridine; Cdk 1, Cyclin dependent kinase 1; CYP, cytochrome P450; DEVD-AMC, N-acetyl-Asp-Glu-Val-Asp-aminomethylcoumarin; EGF, epidermal growth factor; EROD, ethoxyresorufin O-deethylase; 3-MC, 3-methylcholantrene; β-NF, β-naphtoflavone; PB, phenobarbital; and PROD, pentoxyresorufin O-depentylase. |
Auteur: |
De Smet, Karen Loyer, Pascal Gilot, David Vercruysse, Antoine Rogiers, Vera Guguen-Guillouzo, Christiane |
Verschenen in: |
Biochemical pharmacology |
Paginering: |
Jaargang 61 (2001) nr. 10 pagina's 11 p. |
Jaar: |
2001 |
Inhoud: |
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Uitgever: |
Elsevier Science Inc. |
Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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