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ADP-induced platelet aggregation and inhibition of adenylyl cyclase activity stimulated by prostaglandins∗ ∗ Abbreviations: ADP-β-S, adenosine 5′-O-(2-thiodiphosphate); ADP-α-S, adenosine 5′-S-(2-O-diphosphate); PLA2, phospholipase A2; cPLA2, cytosolic phospholipase A2; PLC, phospholipase C; PKC, protein kinase C; CO, cyclooxygenase; TS, thromboxane synthetase; MAPK, mitogen activated protein kinase; αIIbβ3 or GPIIb-IIIa, glycoprotein IIb-IIIa complex; GPIb-IX-V complex, a complex of glycoproteins Ib, IX, and V; PC, phosphatidylcholine; AA, arachidonic acid; TXA2, thromboxane A2; DAG, diacylglycerol; IP3, inositol (1,4,5)-triphosphate; PGG2, prostaglandin G2; PGH2, prostaglandin H2; CTX, cholera toxin; PTX, pertussis toxin; 2-MeS-ADP, 2-methylthioadenosine 5′-diphosphate; 2-N3-ADP, 2-azidoadenosine 5′-diphosphate; and 2-AzPET-ADP, 2-(p-azidophenyl) ethylthioadenosine 5′-diphosphate. |
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Titel: |
ADP-induced platelet aggregation and inhibition of adenylyl cyclase activity stimulated by prostaglandins∗ ∗ Abbreviations: ADP-β-S, adenosine 5′-O-(2-thiodiphosphate); ADP-α-S, adenosine 5′-S-(2-O-diphosphate); PLA2, phospholipase A2; cPLA2, cytosolic phospholipase A2; PLC, phospholipase C; PKC, protein kinase C; CO, cyclooxygenase; TS, thromboxane synthetase; MAPK, mitogen activated protein kinase; αIIbβ3 or GPIIb-IIIa, glycoprotein IIb-IIIa complex; GPIb-IX-V complex, a complex of glycoproteins Ib, IX, and V; PC, phosphatidylcholine; AA, arachidonic acid; TXA2, thromboxane A2; DAG, diacylglycerol; IP3, inositol (1,4,5)-triphosphate; PGG2, prostaglandin G2; PGH2, prostaglandin H2; CTX, cholera toxin; PTX, pertussis toxin; 2-MeS-ADP, 2-methylthioadenosine 5′-diphosphate; 2-N3-ADP, 2-azidoadenosine 5′-diphosphate; and 2-AzPET-ADP, 2-(p-azidophenyl) ethylthioadenosine 5′-diphosphate. |
Auteur: |
Puri, Rajinder N. |
Verschenen in: |
Biochemical pharmacology |
Paginering: |
Jaargang 57 (1999) nr. 8 pagina's 9 p. |
Jaar: |
1999 |
Inhoud: |
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Uitgever: |
Elsevier Science Inc. |
Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
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