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Details for article 6 of 7 found articles
| Title: |
The characterization of a non-Newtonian blood analog in natural- and shear-layer-induced transitional flow |
| Author: |
Li, Lin Walker, Andrew M. Rival, David E. |
| Appeared in: |
Biorheology |
| Paging: | Volume 51 (2014) nr. 4-5 pages 275-291 |
| Year: |
2014-10-03 |
| Contents: |
BACKGROUND: Although a blood analog of aqueous glycerol and xanthan gum was found to replicate the viscoelastic behavior of blood, measurements were restricted to laminar flow. OBJECTIVE: To expand the characterization of a non-Newtonian blood analog of aqueous glycerol and xanthan gum to transitional Reynolds numbers to quantify its behavior as a function of both natural and shear-layer-induced mechanisms. METHODS: A Newtonian analog and a shear-thinning aqueous glycerol, xanthan gum solution were circulated through an in vitro flow loop replicating both a straight and obstructed artery where transition was initiated through natural and shear-layer-induced mechanisms respectively. Steady and pulsatile pressure drop measurements for both fluids were acquired across a range of Reynolds numbers up to 7600 and Womersley numbers of 4 and 6. RESULTS: In steady and pulsatile straight flow, the non-Newtonian analog presented with reduced pressure drops and prolonged laminar flow to Reynolds numbers of 3200 and 3800 respectively. Upon blockage inclusion, non-Newtonian minor losses were comparable to Newtonian in steady flow and greater in pulsatile flow suggesting an elongation of downstream non-Newtonian recirculation. Although non-Newtonian total system pressure drops in both straight and obstructed flows were lower, the ratio of pressure drop difference between the two fluids decreased through shear-layer-induced transition. CONCLUSIONS: These findings not only demonstrated the suitability of using a xanthan gum analog to model blood flow in transitional regimes, but also presented the respective differences in analog behavior as a function of transition mechanism. |
| Publisher: |
IOS Press |
| Source file: |
Elektronische Wetenschappelijke Tijdschriften |
Details for article 6 of 7 found articles
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