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| Titel: |
New information from cell aggregate compression tests and its implications for theories of cell sorting |
| Auteur: |
G. Wayne Brodland |
| Verschenen in: |
Biorheology |
| Paginering: | Jaargang 40 (2002) nr. 1-3 pagina's 273-277 |
| Jaar: |
2002-10-28 |
| Inhoud: |
In order to verify theories about the mechanics of cell sorting, tissue spreading and checkerboard pattern formation, it is necessary to measure certain cell properties such as surface tension and adhesiveness. The purpose of this work is to clarify the relationship between these two important properties and to use computer simulations and analytical calculations to extract additional information from parallel plate compression tests. This paper shows that compression tests can be used to determine not only the surface tension between the aggregate and the surrounding medium, but also the effective viscosity of the cell cytoplasm and the interfacial tension that acts between the cells that make up the aggregate. The findings reported here also support a novel, differential interfacial tension-based theory for cell sorting, tissue spreading and checkerboard pattern formation, and pose further challenges to current differential adhesion-based models. |
| Uitgever: |
IOS Press |
| Bronbestand: |
Elektronische Wetenschappelijke Tijdschriften |
Details van artikel 41 van 57 gevonden artikelen
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